Open Chemistry Journal

2 : 40-46
Published online 2015 December 14. DOI: 10.2174/1874842201502010040
Publisher ID: CHEM-2-40

RESEARCH ARTICLE
A Facile Synthesis of ()-2-((5-(4-fluorobenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl) amino) Substituted Acid Using Microwave Irradiation and Conventional Method

Dattatraya N. Pansare and Devanand B. Shinde, *
Department of Chemical Technology, Babasaheb Ambedkar Marathwada University, Aurangabad 431 004, India.

* Address correspondence to this author at the Department of Chemical Technology, Babasaheb Ambedkar Marathwada University, Aurangabad 431 004, India; Tel No.:+91 0240-2403308; Fax No.: +91 0240-2400413; E-mail: dbsdattatraya10@rediffmail.com

ABSTRACT

A new effective approach to the synthesis of some new (Z)-2-((5-(4-fluorobenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)amino) substituted acid 6a-l is reported under microwave irradiation as well as conventional conditions.

Keywords:

Amino acids, Knoevenagel condensation, Microwave irradiation, Rhodanine.