Open Chemistry Journal

2018, 5 : 76-88
Published online 2018 September 28. DOI: 10.2174/1874842201805010076
Publisher ID: CHEM-5-76

REVIEW ARTICLE
C-C Forming Reactions with Palladium and Platinum: Lessons Learned in Our Group

Areej Hashim1 , Abdullah Al-Hemyari1 , Muna Bufaroosha1 , Masataka Watanabe2 , Krishna G. Dongol2 and Thies Thiemann1, *
1 Department of Chemistry, College of Science, United Arab Emirates University, PO Box 15551, Al Ain, United Arab Emirates
2 Graduate School of Engineering and Institute of Materials and Chemical Engineering, , ,

* Address correspondence to this author at the Department of Chemistry, College of Science, United Arab Emirates University, PO Box 15551, Al Ain, United Arab Emirates; Tel: +971-(0)56-692-5943; E-mail: thies@uaeu.ac.ae

ABSTRACT

This short paper details our experiences with Pd- and Pt-catalyzed cross-coupling and cyclization reactions in investigations covering the years from 1997 until now. Pd-catalysed Suzuki-Miyaura-, Heck- and Sonogashira-type cross coupling reactions in conjunction with other transformations in one pot, especially with the Wittig reaction, are highlighted. This is followed by a description of a combination of Heck- and cyclization reactions. Finally, Pt-catalyzed diene-yne cyclization reactions are discussed.

Keywords:

Suzuki-Miyaura reaction, Wittig olefination, Heck reaction, Sonogashira coupling, Diene-yne cyclization, Triene cyclization, Pd-catalysis, Pt-catalysis.