The Open Allergy Journal

2009, 2 : 27-29
Published online 2009 June 18. DOI: 10.2174/1874838400902010027
Publisher ID: TOALLJ-2-27

Characterization of the Group I Allergen of Bahia Grass Pollen

J. M. White , A. Majidi , S. A. Naser , M. J. Sweeney and R. S. White
Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL. USA.

ABSTRACT

Four allergenic proteins of Bahia (BA) grass pollen with estimated molecular weights of 45, 33, 31 and 28 kD were previously detected. Although all four proteins were reactive with BA grass allergic patient sera, the 33kD component was previously verified as a major allergen. The investigators report here for the first time, the similarities between the group I 33 kD allergen of BA grass, Pas n 1, and Group I allergen of Timothy grass, Phl p 1, using N-terminal amino acid sequencing and monoclonal antibodies, IG12 and BOT14, made to Timothy Phl p 1.