The Open Breast Cancer Journal

2011, 3 : 45-48
Published online 2011 December 09. DOI: 10.2174/1876817201103010045
Publisher ID: TOBCANJ-3-45

Malignant Phyllodes Tumor of the Breast: A Case Report

Mohammed Al-Zoubaidi , Suimin Qiu , Mark Bonnen , Melissa Joyner , Kendall Roehl , Colleen Silva and Celia Chao
Department of Surgery, University of Texas Medical Branch, 301 University Boulevard, Galveston, Texas 77555, USA.

ABSTRACT

Phyllodes tumors of the breast have biphasic histological features with both epithelial and stromal components. Careful characterization of the stromal compartment is critical since it is the pathologic features of the stromal cells that determine its malignant potential. We present a case report of a woman with an aggressive malignant phyllodes tumor with sarcomatous differentiation, who succumbed to metastatic disease within 8 months of initial presentation.