The Open Bioactive Compounds Journal

2009, 2 : 8-16
Published online 2009 January 29. DOI: 10.2174/1874847300902010008
Publisher ID: TOBCJ-2-8

RESEARCH ARTICLE
Hydrazonoyl Halides: Their Versatile Biological Activities

Ahmad S.Shawalia, * and Nevien A.Samyb
a Department of Chemistry, Faculty of Science, University of Cairo, Giza, Egypt;
b Department of Dermatology, National Institute of Laser Enhanced Sciences, University of Cairo, Giza, Egypt

* Address correspondence to this author at the Department of Chemistry, Faculty of Science, University of Cairo, Giza, Egypt; E-mail: as_shawali@yahoo.com

ABSTRACT

The various biological activities namely anthelmintic, antiarthropodal, antiviral, antimicrobial, herbicidal, antisarcoptic, acaricidal, insecticidal and miticidal activities exhibited by the hydrazonoyl halides are surveyed. Also, the uses of such halides as pesticides, weed controlling and antihypertensive agents as well as lipoxygenase and cyclo-oxygenase inhibitors are presented. Furthermore, their contact dermatitis and phytotoxicity effects are pointed out in addition to their metabolic fate.

Keywords :

Hydrazonoyl halides, biological activities, metabolism.