The Open Chemical and Biomedical Methods Journal

2010, 3 : 46-55
Published online 2010 November 1. DOI: 10.2174/1875038901003010046
Publisher ID: TOCBMJ-3-46

Chiral Analyses of Pollutants by Capillary Electrophoresis

Imran Ali , Tabrez A. Khan , Hassan Y. Aboul-Enein , Igor B. Kuznetsov and Asim Mohd
(IA) Department of Chemistry, Jamia Millia Islamia (Central University), New Delhi – 110025, India.

ABSTRACT

The determination of enantiomeric composition of chiral xenobiotics and pollutants is a very difficult job due to their low amounts and poor detection by commonly used UV detector. But this sort of analysis is an important issue from the health point of view. The chiral analyses of these notorious pollutants by capillary electrophoresis have been discussed in this article. This review discusses the new trends and advancements, which have been achieved in the analyses of chiral pollutants using capillary electrophoresis and the state-of-art of their enaniomeric resolution. This article focuses on sample treatment, applications, optimization, detection, mechanisms of chiral resolution and future perspectives of CE in chiral resolution of xenobiotics. Besides, efforts have also been made to suggest the improvement in CE machine to make it ideal for the analyses of chiral xenobiotics at trace levels.

Keywords:

Capillary electrophoresis, environmental pollutants and xenobiotics, nanoscale analyses, optimization, future perspectives.