The Open Chemical and Biomedical Methods Journal

2010, 3 : 56-73
Published online 2010 November 1. DOI: 10.2174/1875038901003010056
Publisher ID: TOCBMJ-3-56

The Analytical Applications of Square Wave Voltammetry on Pharmaceutical Analysis

Burcu Dogan-Topal , Sibel A. Ozkan and Bengi Uslu
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06100, Tandogan, Ankara, Turkey.

ABSTRACT

Compared to other voltammetric techniques a square wave voltammetry (SWV), which is presented in this minireview, has a several advantages such as high speed, increased analytical sensitivity and relative insensitivity to the presence of dissolved oxygen. Also it is an electrochemical technique used in analytical applications and fundamental studies of electrode mechanism. This paper delivers both the underlying theory and the practical guidance needed to apply square wave techniques and also provides a wide collection of data for the description of diverse tendencies that characterize several electrochemical reactions analyzed by SWV. This review summarizes some of the recent developments and application of direct and stripping SWV for drug compounds in their dosage forms and biological samples as reported in the period from 1997 till 2010 year.

Keywords:

Square wave voltammetry, electrochemistry, drug analysis, nanoscale determination, electrode design.