The Open Chemical and Biomedical Methods Journal

2010, 3 : 74-85
Published online 2010 November 1. DOI: 10.2174/1875038901003010074
Publisher ID: TOCBMJ-3-74

Electrochemistry of Cyclodextrin Inclusion Complexes of Pharmaceutical Compounds

Abd-Elgawad Radi and Shimaa Eissa
Department of Chemistry, Faculty of Science (Dumyat), Mansoura University; 34517 Dumyat, Egypt.

ABSTRACT

Electrochemistry of cyclodextrins (CDs) and cyclodextrin inclusion complexes with different pharmaceutical compounds is reviewed. The article highlights some electrochemical investigations of the CD-drugs interactions in solution. Cyclodextrin modified electrodes and their applications as electrochemical sensors in pharmaceutical analysis based on the self-assembly of CD derivatives on metal electrodes and nanoparticles, and cyclodextrin-modified multiwalled carbon nanotubes are also discussed.

Keywords:

Cyclodextrins, pharmaceutical, electrochemical sensors, nanoscale determination, modified electrodes.