The Open Critical Care Medicine Journal

2011, 4 : 24-27
Published online 2011 July 07. DOI: 10.2174/1874828701104010024
Publisher ID: TOCCMJ-4-24

Motor Neuron Diseases and Myopathies: Implications for Perioperative Management and Intensive Care

Tino Prell and Julian Grosskreutz
Hans-Berger Department of Neurology, Friedrich-Schiller-University Hospital Jena, Erlanger Allee 101, D-07747 Jena, Germany.

ABSTRACT

Motor neuron diseases like amyotrophic lateral sclerosis and myopathies are associated with a higher risk of cardiac and respiratory complications, especially during operative procedures. This review gives an overview of the various complications from which patients with motor neurone diseases and muscular dystrophies may suffer during operations and anaesthesia. The main focus is on the pathophysiological aspects as well as the diagnoses of typical cardiac and respiratory complications, their prevention, and their management.

Keywords:

Neuromuscular disease, respiratory failure, cardiac involvement, amyotrophic lateral sclerosis, muscular dystrophies, non-invasive ventilation, intensive care.