The Open Critical Care Medicine Journal

2013, 6 : 46-55
Published online 2013 December 27. DOI: 10.2174/1874828701306010046
Publisher ID: TOCCMJ-6-46

Blood Pressure Control in Neurological ICU Patients: What is Too High and What is Too Low?

Gulrukh Zaidi , Astha Chichra , Michael Weitzen and Mangala Narasimhan
Division of Pulmonary, Critical Care and Sleep Medicine, The North Shore, Long-Island Jewish Health System, The Hofstra-North Shore LIJ School of Medicine, USA.

ABSTRACT

The optimal blood pressure (BP) management in critically ill patients with neurological emergencies in the intensive care unit poses several challenges. Both over and under correction of the blood pressure are associated with increased morbidity and mortality in this population. Target blood pressures and therapeutic management are based on guidelines including those from the American Stroke Association and the Joint National Committee guidelines. We review these recommendations and the current concepts of blood pressure management in neurological emergencies. A variety of therapeutic agents including nicardipine, labetalol, nitroprusside are used for blood pressure management in patients with ischemic and hemorrhagic strokes. Currently, the role of inducing hypertension remains unclear. Hypertensive crises include hypertensive urgencies where elevated blood pressures are seen without end organ damage and can usually be managed by oral agents, and hypertensive emergencies where end organ damage is present and requires immediate treatment with intravenous drugs.

Keywords:

Ischemic stroke, hemorrhagic stroke, hypertension.