The Open Crystallography Journal
2010, 3 : 16-28Published online 2010 March 25. DOI: 10.2174/1874846501003010016
Publisher ID: TOCRYJ-3-16
Thiosemicarbazone Metal Complexes: From Structure to Activity
Dipartimento di Chimica Generale e Inorganica, Chimica Analitica, Chimica Fisica, viale GP Usberti
17a, 43124 Parma, Italy.
ABSTRACT
Thiosemicarbazones and their metal complexes are compounds that possess antitumor, antibacterial, antifungal and antiviral properties. For the foremost majority of cases the activity of the ligand is greatly enhanced by the presence of a metal ion. The most relevant papers recently published are reviewed with an attempt to find a relationship between common structural features and activity.