The Open Clinical Trials Journal

2011, 3 : 20-25
Published online 2011 November 11. DOI: 10.2174/1876821001103010020
Publisher ID: TOCTJ-3-20

RESEARCH ARTICLE
Diabetic Gastrointestinal Neuropathy: Elusive Diagnosis and Difficult Treatment

Patrizio Tatti, *,1 , Felice Strollo2 and Annabel Barber3
1 Endocrinology and Diabetes Unit – ASL RMH, Roma, Italy
2 Istituto INRCA, Roma, Italy
3 University of Nevada, Las Vegas, USA

* Address correspondence to this author at the Diabetes and Endocrinology Unit - ASL RMH, Italy; Tel:+390693273094; Fax:+39063218855; E-mails: , info@patriziotatti.it

ABSTRACT

Diabetic Gastrointestinal Neuropathy is an elusive diagnosis and often overlooked. The affected patients do not connect the symptoms with diabetes and undergo a painstaking and expensive search for other disorders of the digestive tract. Diabetic Gastrointestinal Neuropathy additionally causes a baffling glucose instability that further aggravates the condition. The treatment is difficult. The less severe cases respond to prokinetic treatment, but when the disease is advanced the only available therapy is the insertion of a pacemaker

Keywords:

Diabetic gastrointestinal neuropathy, glucose variability, gastrointestinal pacemaker.