The Open Diabetes Journal

2018, 8 : 22-33
Published online 2018 August 31. DOI: 10.2174/1876524601808010022
Publisher ID: TODIAJ-8-22

SYSTEMATIC REVIEW
 Type 2 Diabetes Treatment and Drug Development Study

Da-Yong Lu1, * , Jin-Yu Che1 , Nagendra Sastry Yarla2 , Hong-Ying Wu1 , Ting-Ren Lu1 , Bin Xu3 , Shu-Yun Wu3 , Jian Ding3 , Yi Lu4 and Hong Zhu5
1 , ,
2 Divisions of Biochemistry and Chemistry, City University of New York School of Medicine, 160 Convent Avenue, , NY 10031,
3 Shanghai Institute of Materia Medica, , ,
4 , ,
5 College of Pharmaceutical Science, , ,

* Address correspondence to this author at the Shanghai University, Shanghai, P. R. China; Email: ludayong@shu.edu.cn

ABSTRACT

The causality and etio-pathologic risks for patients with Type 2 Diabetes (T2DM) are important areas in modern medicine. Disease complications are largely unpredictable in patients with T2DM. In the future, we welcome therapeutics of both cutting-edge and traditional for anti-diabetic treatments and management with higher efficiency and less cost. Expanding medical knowledge, behavior/life-style notification in healthcare, modern genetic/bioinformatics diagnostic promotion, clinical developments (Traditional Chinese Medicine and personalized medicine) and new drug developments - including candidate drug targets should be implemented in the future. These efforts might be useful avenues for updating anti-diabetic therapeutics globally. This article aims at introducing this information for T2DM treatment boosts.

Keywords:

Diabetes Mellitus, Diabetes therapy, Medical education, Type 2 diabetes, Insulin-derivatives, Bee extract, Cardiovascular complication, Hyperglycemia, Traditional Chinese Medicine.