Open Glycoscience

2012, 5 : 31-40
Published online 2012 May 4. DOI: 10.2174/1875398101205010031
Publisher ID: TOGLYJ-5-31

Glyco-silicon Functional Materials as Anti-influenza Virus Agents

Koji Matsuoka , Tetsuo Koyama and Ken Hatano
Area for Molecular Function, Division of Materials Science, Graduate School of Science and Engineering, Saitama University, Sakura, Saitama 338-8570, Japan.

ABSTRACT

This review shows introduction of glycoclusters using carbosilanes as core scaffolds, preparations of glyco-clusters and their excellent properties as well as functions. Since a dendrimer has unique advantages such as single mo-lecular weight, regularity of structure and easy control of shape and size, dendrimers are utilized in various research areas. Results of syntheses and biological evaluations of the carbosilane dendrimers having carbohydrate moieties for influenza viruses are presented.

Keywords:

Dendrimers, Carbosilanes, Carbohydrates, Glycodendrimers, Influenza viruses.