The Open Hypertension Journal

2013, 5 : 49-49
Published online 2013 November 15. DOI: 10.2174/1876526201305010049
Publisher ID: TOHYPERJ-5-49

Cardiometabolic Factors and Breast Cancer: A Case-Control Study in Women

Niki Mourouti , Christos Papavagelis , Meropi D. Kontogianni , Petrini Plytzanopoulou , Tonia Vassilakou , Nikolaos Malamos , Athena Linos and Demosthenes B. Panagiotakos
46 Paleon Polemiston St., Glyfada, Attica, 166 74, Greece.

ABSTRACT

Background:

Previous studies have suggested that individual cardiometabolic factors may be associated with an increased risk of breast cancer.

Objective:

To evaluate the association between individual cardiometabolic factors with breast cancer development.

Design:

A case – control study. Two-hundred-and-fifty consecutive, newly diagnosed breast cancer female patients (56±12 years) and 250, one-to-one age-matched with the patients, healthy volunteers (controls), were studied. A standardized, validated questionnaire assessing various socio-demographic, clinical, lifestyle and dietary characteristics, was applied through face-to-face interviews. Adherence to the Mediterranean diet was evaluated using the 11-components MedDietScore (theoretical range 0-55). A detailed medical history regarding the common co-morbidities (i.e., diabetes, hypertension, hypercholesterolemia) and their treatment was also recorded, while women were also categorized using the Body Mass Index (BMI) as an indicator of obesity.

Results:

Obesity (i.e., BMI>30 kg/m2) was positively associated with the likelihood of having breast cancer.

Conclusions:

With the exception of obesity, none of the other tested cardiometabolic risk factors seemed to be a predisposing factor for breast cancer development.

Keywords:

Cardiometabolic factors, diabetes, .