The Open Lung Cancer Journal

2010, 3 : 34-37
Published online 2010 July 20. DOI: 10.2174/1876819901003010034
Publisher ID: TOLCJ-3-34

Anemia in Elderly Sudanese Lung Cancer Patients Treated with Chemotherapy

Fathelrahman Mahdi Hassan and Eman A. Weeda
College of Medical Laboratory Science, Sudan University of Science and Technology, Khartoum, Sudan.

ABSTRACT

Background:

Cancer among Sudanese citizens has been rapidly rising since 1999 till this year and at least 80% of all patients undergo chemotherapy will develop anemia as a complication of these drugs.

Aim:

To publish the Sudanese patients Hemodynamic observations during various regimen of Chemotherapy in lung cancer.

Settings and Design:

This prospective observational study was conducted in the major specialized medical Radiation and Isotope Center Khartoum (RICK).

Materials and Methods:

Eighty patients diagnosed of having lung cancer admitted from June 2008 to September 2009. Patients enrolled in the study were required to be ≥60 years old and to have a confirmed diagnosis of lung cancer, for which they were undergoing concomitantly radio - chemotherapy.

Statistical Analysis:

Analysis of data obtained by independent sample test (t-test) was performed for equality of these mean probability value.

Results:

Prior treatment pre cycle I; 56.2% of patients were normal, 38.8% with mild anemia and 5.0% were had a moderate anemia. Post cycle I treatment; the normal were declined to only 9.0% and mild anemia were the highest percentage 55% followed by 28.5% for moderate anemia and 7.5% showed severe anemia. Post cycle II about 27.5% of patient showed normal hemoglobin while the majority of them 72.5% had moderate anemia.

Conclusion:

A correlation of hemoglobin values after completion of therapy to overall treatment was found as a decline in range of (1 to 2 g/dl). Anemia has been demonstrated to be a predictive indicator of response to chemo radiotherapy in lung tumors.

Keywords:

Cancer, lung cancer, therapy, anemia.