Prenatal Diagnosis of Fetal Arrhythmias and Assessment of Autonomic Nervous System Activity by Fetal Magnetocardiography

ABSTRACT

Magnetocardiography (MCG) is a technique that enables the noncontact, noninvasive measurement of electrocardiographic phenomena, and fetal magnetocardiography (FMCG) is extremely useful for the analysis of fetal electrocardiographic phenomena. We have used FMCG for the diagnosis and treatment of a range of fetal arrhythmias, and to perform comparative studies of autonomic nervous system activity in fetuses with normal growth and those with fetal growth restriction by analyzing fetal heart rate variability. In terms of fetal arrhythmias, fatal long QT syndrome was accurately diagnosed prenatally using FMCG, and pregnancy was maintained until delivery at 37 weeks gestation. With regard to fetal autonomic nervous system activity, there was a pronounced increase in sympathetic nervous activity among fetuses with normal growth in the second half of pregnancy.

Keywords:

Fetus, arrhythmias, autonomic nervous system activity, fetal growth restriction, magnetocardiography, prenatal diagnosis, long QT syndrome.