The Open Nanoscience Journal

2011, 5 : 78-82
Published online 2011 December 21. DOI: 10.2174/1874140101105010078
Publisher ID: TONANOJ-5-78

Synthesis and Morphological Study of Aminoglycosides-Modified Gold and Silver Nanoparticles

Santosh V. Nalage , Sidhanath V. Bhosale and Sheshanath V. Bhosale
Department of Organic Chemistry, North Maharashtra University, Jalgaon 425 001 (MS) India.

ABSTRACT

We demonstrate new method for the synthesis of gold and silver nanoparticles from pineapple extract. Furthermore, we have studied interactions between nanoparticles (gold and silver) with aminoglycosides such as Kanamycin A, Neomycin. Both nanoparticles were prepared by reducing AuCl4 and AgNO3 using pineapple extract, kanamycin A and neomycin as both reducing and stabilizing agents respectively. Our new approach shows a clean method of synthesizing gold and silver nanoparticles that exhibit promising morphologies and stability under physiological conditions for several months in powder or aqueous form. Transmission electron microscopy (TEM) was employed to visualize the diameters of nanoparticles.