Long-Term Follow-Up and Clinico-Histopathological Features of Simpson Grade 1 Surgical Resection of Large Olfactory Groove Meningioma

ABSTRACT

Olfactory groove meningiomas can attain substantial size before producing enough symptoms alerting the patient or physician to the possibility of a tumor. The surgical goal is gross total resection in order to reduce the chances of recurrence, however, increased surgical complication rates can be seen with more aggressive resections. The optimal imaging follow-up time following gross total resection of olfactory groove meningiomas is not known. We report a young woman presenting with a three year history of frontal lobe dysfunction, anosmia and bitemporal visual field loss harboring a massive olfactory groove meningioma. She underwent gross total resection of a tumor with unusual neuropathological features potentially worrisome for aggressive behavior. Ten year follow-up with annual imaging has demonstrated no evidence of recurrence. The current literature on olfactory groove meningiomas following Simpson grade 1 resection regarding the various surgical approaches, complication and recurrence rates is reviewed. Unique features of this case suggest that ongoing surveillance may be necessary.