The Open Natural Products Journal
2010, 3 : 1-5Published online 2010 January 19. DOI: 10.2174/1874848101003010001
Publisher ID: TONPJ-3-1
Protoxylogranatin B, a Key Biosynthetic Intermediate from Xylocarpus granatum: Suggesting an Biogenetic Pathway to Limonoid
Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China.
ABSTRACT
Protoxylogranatin B, a new protolimonoid identified from the seeds of a Chinese mangrove, Xylocarpus granatum, was proposed as the key biosynthetic intermediate. Its structure was established on the basis of spectroscopic techniques, including 1H - 1H COSY, HSQC, HMBC and NOESY spectra. The finding of this compound suggested an oxidative cleavage biogenetic pathway from protolimonoid to limonoid.