The Open Nutraceuticals Journal

2012, 5 : 213-218
Published online 2012 December 28. DOI: 10.2174/1876396001205010213
Publisher ID: TONUTRAJ-5-213

Computational Studies and Molecular Dynamics of the Potent Biochemical and Molecular Markers in Relevance to Oral Cancer

Rashi Srivastava , Rolee Sharma , R.B. Singh , Douglas W. Wilson and Sanjay Mishra
School of Biotechnology IFTM University Lodhipur Rajput, Delhi Road (NH-24), Moradabad 244 001, U.P., India.

ABSTRACT

Oral cancer is the uncontrolled tissue growth observed in the oral cavity. It may arise as a consequence of me-tastasis and/or by extension from a neighboring anatomic structure, such as the nasal cavity or the maxillary sinus. In view of putative biochemical exploration on oral carcinoma and development of certain nutraceuticals viz. omega 3 versus 6 fatty acids, cancer protective vitamins, probiotics, antioxidants, oral enzymes and mineral mainly selenium based on the hypothesis projected by non-conventional laboratory study, the present work on molecular dynamics of oral cancer was undertaken. The data thus obtained provide new insights into exploring major biochemical and/or molecular markers probably involved in diagnostics as well as therapeutics concerned with the oral carcinoma.

Keywords:

Bioinformatics, Neoplasia, Oncogenes.