The Open Nutrition Journal

2017, 11 : 11-16
Published online 2017 January 31. DOI: 10.2174/1874288201711010011
Publisher ID: TONUTRJ-11-11

RESEARCH ARTICLE
 The Efficacy of Curcumin on Cognition, Depression, and Agitation in Older Adults with Alzheimer’s Disease

Jyotsna Sharman1, * , Roofia Galeshi2 , Lisa Onega3 , Susanne Ashby4 and Kavya Sharman5

*Address correspondence to this author at the Department of Health and Human Performance, Radford University, Radford, VA, USA; Tel: Home: (870) 210-2522; Fax: (540) 831-6650; E-mail: jsharman2@radford.edu

ABSTRACT

The purpose of this systematic review was to ascertain the current state of science regarding the use of turmeric and its pigment curcumin in individuals with Alzheimer’s Disease (AD). A summary of qualitative and quantitative evidence specific to the effect of curcumin on AD is presented in this article. The purpose of the review was to evaluate and summarize findings related to this body of research. Findings indicated a positive correlation between administration of turmeric and improvement AD symptoms; however, long-term benefits need to be researched. Also, experimental research with older adults with mild, moderate, and severe AD should be conducted to determine whether or not turmeric and curcumin improve cognition, depression, and agitation. Specific methodological issues that need to be considered are the dosage and purity of turmeric and curcumin, administration frequency, determination of a suitable placebo, and duration of testing.

Keywords:

Curcumin, Cognition, Depression, Older Adults, Alzheimer’s Disease, Dementia.