The Open Organic Chemistry Journal

2008, 2 : 88-91
Published online 2008 August 24. DOI: 10.2174/1874095200801020088
Publisher ID: TOOCJ-2-88

Chromone-3-carboxaldehydes in Passerini Reactions Using TosMIC as the Isonitrile Component

Michael A. Terzidis , Julia Stephanidou-Stephanatou and Constantinos A. Tsoleridis
Department of Chemistry, Laboratory of Organic Chemistry, University of Thessaloniki, Thessaloniki 54124, Greece.

ABSTRACT

p-Toluenesulfonylmethyl isocyanide (TosMIC) is used as the isonitrile component in Passerini reactions with chromone-3-carboxaldehydes to yield chromenyl-amidoesters in good yields.

Keywords:

Chromenyl-acetamides, chromone-3-carboxaldehydes.