The Open Organic Chemistry Journal

2013, 7 : 15-20
Published online 2013 November 29. DOI: 10.2174/1874095201307010015
Publisher ID: TOOCJ-7-15

Palladium-Catalyzed Synthesis of Trimethylsilyl Substituted Benzopyran Derivatives

Yanmei Zhang , Wei-Xing Dan , Jianqi Liu , Micky D. Tortorella , Zhengchao Tu and John J Talley
Drug Discovery Pipeline, Guangzhou Institute of Biomedicine and Health, Science City, Guangzhou, 510530, P. R. China.

ABSTRACT

Palladium catalysis is an efficient way to obtain trimethylsilyl substituted benzopyran derivatives. After screening a series of reactions , we found optimized conditions.

Keywords:

Palladium-catalyzed, benzopyran, trimethyl silylation.