Pharmaceutical Crops

2012, 3 : 7-37
Published online 2012 January 16. DOI: 10.2174/2210290601203010007
Publisher ID: TOPHARMCJ-3-7

Anthocyanins and Flavonoids of Vaccinium L.

Zushang Su
National Center for Pharmaceutical Crops, Arthur Temple College of Forestry and Agriculture, Stephen F. Austin State University, Nacogdoches, TX 75962, USA.

ABSTRACT

Vaccinium L., comprising approximately 450 species primarily in the Northern Hemisphere, is a genus of shrubs or lianas in the family Ericaceae. The berries of many species are harvested for household consumption and commercial sale. The genus produces a wide range of compounds such as anthocyanins, flavonoids, chromones, coumarins, lignans, benzoic acids, iridoids, sterols, and triterpenoids, but is best known for the production of anthocyanins and flavonoids. Extracts and isolates of anthocyanins and flavonoids from Vaccinium fruits or leaves showed antioxidative, anti-inflammatory, antitumor, antiviral, vasoprotective, and antifungal activities. To data, more than 116 anthocyanins and flavonoids compounds have been isolated and identified primarily from the fruits or leaves of Vaccinium. This article reviews phytochemistry and pharmaceutical properties of these compounds.