The Open Conference Proceedings Journal

2012, 3 : 6-11
Published online 2012 July 12. DOI: 10.2174/1876326X01203020006
Publisher ID: TOPROCJ-3-3-6

The First Isoenzymatic Characterizations of the Leishmania Strains Responsible for Cutaneous Leishmaniasis in the Area of Annaba (Eastern Algeria)

Roukaya Mansouri , Francine Pratlong , Fatma Bachi , Boussad Hamrioui and Jean Pierre Dedet
Service de Parasitologie-Mycologie , Hopital IBN SINA, CHU Annaba, Algerie.

ABSTRACT

The epidemiological situation of cutaneous leishmaniasis in the region of Annaba (North Eastern Algeria) is explored for the first time. During a clinical survey carried out in the Annaba Hospital between 2004 and 2008, the parasi-tological study of lesions has revealed 259 positive cases (43.31%). Isoenzymatic identification of 16 strains isolated showed the presence of three Leishmania species and four zymodemes. The hypothesis of the presence of L. infantum is confirmed with two zymodemes, MON-1 and MON-24. The unexpected presence of L. major MON-25 certifies the sub-stantial extension of this zoonotic form to the North. The isolation of L.killicki, whose presence was unsuspected, reiter-ated the interest of eco-epidemiological analysis of households affected by the disease. Moreover, it is a new zymodeme never isolated so far, the MON-306.

Keywords:

Annaba, Algeria, Cutaneaous leishmaniases.