The Open Conference Proceedings Journal
2013, 4 : 72-76Published online 2013 October 30. DOI: 10.2174/2210289201304010072
Publisher ID: TOPROCJ-4-3-72
Anti Malarial Activity of Cassia Sieberiana Leaf Extracts
ABSTRACT
This research was carried out to determine the antimalarial efficacy of Cassia sieberiana against Plasmodium parasites isolated from patients attending Nassarawa Specialist Hospital, Kano Nigeria. The research revealed that the leaf extracts of C. sieberiana are highly effective in killing Plasmodium parasite belonging to falciparum species. It was also established that the extracts are not harmful and are safe for human consumption. Accordingly, the study recommended pharmacological screenings with fractions of methanol extract as well as the isolation and identification of active compounds from the plant. The leaf extracts of C. sieberiana could be used for antiplasmodial therapy; however, it is imperative to carry out further tests to ascertain the effects on human organs such as heart and liver in order to determine the level of safety.