The Open Conference Proceedings Journal

2013, 4 : 101-101
Published online 2013 March 01. DOI: 10.2174/2210289201304010101
Publisher ID: TOPROCJ-4-4-101

Evaluation the Anti-Inflammatory Activity of Some Eastern Libyan Medicinal Plants

Abdulmottaleb E Zetrini , Hamza M flafel , Sami J Alsabri , Khalid Milad Aburas , Akram E Mohamed , Nouri B. Rmeli and Abdul Gbaj
National Medical Research Centre, Zawia, Libya.

ABSTRACT

Four Libyan medicinal plants Olea Europaea (Oleacea), Cistus Incanus (Cistaceae), Launaea Residifolia (Asteraceae) , Cistus Parviflorus ,Lam (Cistaceae) were collected from EL –jabal EL-akhdar eastern Libya in April 2010 .after identified the plants were extracted using microwave technique by three solvents (methanol-ethyl acetate –hexane ) .these plants were studied for anti-inflammatory activity using carrageenan induced mice odema model. The plant extracts of different solvents were administered at dose 250 mg /kg of the body weight intraperitoneally. among these extracts, Cistus Parviflorus ,Lam extract especially methanolic and ethyl acetate extracts gave the most significant % inhibition of inflammation after 3 hr (57.4±1.9 - 65.5±2.5 respectively) this effect was better than standard reference aspirin (55.1±1.9).

Keywords:

Anti-inflammatory, Olea Europaea, Cistus Incanus, Launaea Residifolia, Cistus Parviflorus, Lam.