Relationship Between Blood Lactate and Oxidative Stress Biomarkers Following Acute Exercise

ABSTRACT

We measured blood lactate, protein carbonyls (PC), and malondialdehyde (MDA) before and immediately after exercise (graded exercise treadmill test [GXT], Wingate cycle sprint, barbell squat, and barbell bench press) in active men. Data were analyzed using a 4 (exercise mode) x 2 (time) ANOVA with Tukey post hoc testing, and pairwise correlations were made. An interaction was noted for lactate (p = 0.009), with values increasing for all modes, and higher post exercise for bench press compared to Wingate and squat (p<0.05). No interaction or exercise mode effect was noted for PC or MDA (p>0.05). However, a time effect was noted for PC (p = 0.02), with values increasing from pre to post exercise. A positive correlation was noted between PC and MDA (r = 0.30; p = 0.0004), however no significant correlations were noted between PC and lactate (r = 0.06; p = 0.51) or between MDA and lactate (r = 0.10; p = 0.22). Blood lactate measured during the immediate post exercise period was not significantly correlated to biomarkers of oxidative stress in active men.