The Open Spectroscopy Journal
2010, 4 : 1-9Published online 2010 January 13. DOI: 10.2174/1874383801004010001
Publisher ID: TOSPECJ-4-1
Improved 1.5 T Magnetic Resonance Spectroscopy in the Human Calf with a Spatially Selective Radio Frequency Surface Coil
ABSTRACT
We describe the use of a transverse field RF surface coil that improves 1.5 T proton MR spectroscopy in the human calf. A 2-element figure-of-eight (FO8) transverse field RF surface coil (diameter 2R=10 cm; separation between the two linear current elements 2s=1cm) and a circular loop (CL) coil of equal diameter where built and tested with proton PRESS spectra at 1.5 T. The 1H PRESS spectra obtained in the resting calf muscle of healthy volunteers showed that the FO8 coil allows a higher PRESS SNR (up to a factor 4.5) within a region of about 20 mm centred at about 12 mm from the coil plane, as compared to a standard CL coil. We found also a faster PRESS SNR decrease in the muscle tissue for anterior/posterior distance > 20 mm using the FO8 coil. The measured PRESS SNR in the fat tissues of the calf showed a signal mostly localised within 10 mm from the coils surface and with an improved SNR (up to 5.5 times) observed in the presence of the FO8 coil as compared to the CL coil of equal diameter. The FO8 coil design can be advantageous for MRS applications, since it allows higher SNR from a small VOI positioned centrally within a relatively narrow region at a given depth in the human calf. The reported spatial SNR features of the FO8 coil design should also be useful for 1H and 31P MRS metabolites quantification in the human brain.