The Open Transplantation Journal

2008, 2 : 73-76
Published online 2008 November 6. DOI: 10.2174/1874418400802010073
Publisher ID: TOTRANSJ-2-73

Epstein-Barr Virus-Negative Lymphoproliferative Disorders after Liver Transplantation

Mitsugi Shimoda , Junji Kita , Masato Kato , Tokihiko Sawada and Keiichi Kubota
Department of Gastroenterological Surgery, Dokkyo University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi 321-0293, Japan.

ABSTRACT

Lymphoproliferative disorders following liver transplantation are often Epstein-Barr virus (EBV)-related highgrade B cell lymphomas. EBV-negative and low-grade lymphoma is a very rare condition after cadaveric as well as living donor liver transplantation (LDLT). Herein we report a case of follicular lymphoma with negative EBV viral capsid antigen (VCA), IgM, IgG and Epstein-Barr virus-encoded small RNA (EBER), which developed after LDLT, and review the literature pertaining to EBV-negative post-transplantation lymphoproliferative disorder (PTLD) after liver transplantation

Keywords:

Follicular lymphoma, living donor liver transplantation, positron emission tomography with computed tomography.