The Open Virology Journal

2007, 1 : 47-50
Published online 2007 December 31. DOI: 10.2174/1874357900701010047
Publisher ID: TOVJ-1-47

RESEARCH ARTICLE
Changing Epidemiology of Rotavirus-Related Hospitalizations in Rio De Janeiro, Brazil, from 2002 to 2006

Vera S Gouvea, *,1 , André L.S Domingues1 , Felipe G Naveca1 , Adriana R Pedro1 and César C Bevilacqua2
1 Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
2 Instituto de Puericultura e Pediatria Martagão Gesteira, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

* Address correspondence to this author at the Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Cidade Universitária, CCS, bloco I, Ilha do Fundão, Rio de Janeiro, RJ 21941-590, Brazil; Tel: (55-21) 2562-6750; Fax: (55-21) 2560-8028; E-mail: vera.gouvea@micro.ufrj.br

ABSTRACT

A prospective hospital-based sentinel study conducted in Rio de Janeiro identified a shift in the pattern (long to short electropherotype and P(8) to P(4) genotype) of rotavirus strains recovered from children with severe diarrhea a few months after the far-reaching Brazilian rotavirus immunization program was launched, posing new interesting challenges.

Keywords:

Rotavirus diarrhea, hospitalizations, genotypes/electropherotypes, vaccine..