The Open Infectious Diseases Journal

2018, 10 : 76-78
Published online 2018 June 18. DOI: 10.2174/1874279301810010076
Publisher ID: TOIDJ-10-76

CASE REPORT
Septicemia and Harlequin Ichthyosis: Outstanding Association

Adil Fouad1, * , Fatiha Bennaoui1 , Nadia El Idrissi Slitine1 , Nabila Soraa2 and FMR Maoulainine1
1 Neonatal Intensive Care Unit, , ,
2 Microbiology Department, , ,

* Address correspondence to this author at the Neonatal Intensive Care Unit, Mohamed VI University Hospital, PB 2360, Ibn Sina Avenue, Marrakesh, Morocco; Tel: +212661046258; Fax: +212524300700; E-mail: adilfouad@hotmail.fr

ABSTRACT

Background:

Harlequin ichthyosis is a rare and fatal fetal disorder, most often complicated by infection. Sepsis due to Vibrio cholerae is rare, especially in neonatology. The association between ichthyosis and Vibrio cholerae infection has never been described in medical literature.

Introduction:

We report the case of a newborn admitted to the neonatal intensive care unit, with a typical characteristics of Harlequin ichthyosis and a sepsis due to Vibrio cholerae, diagnosed with the blood culture. The outcome was fatal; characterized by death six hours after his hospitalization.

Conclusion:

Cases of Harlequin ichthyosis complicated with septicemia with Pseudomonas Aeruginosa have been described. Vibrio cholerae infections are usually confined to the gastrointestinal tract but some species, especially non-01 strains, can cause extra-intestinal infections including septicemia and meningitis.

Keywords:

Harlequin ichthyosis, Infection, Newborn, Septicemia, , .