The Open Pharmacology Journal

2012, 6 : 34-44
Published online 2012 May . DOI: 10.2174/1874143601206010034
Publisher ID: TOPHARMJ-6-34

Intelligent Systems and the Systematization of Pharmacological Knowledge: Application of the In Vitro Retina Model

Vera Maura Fernandes de Lima , Jose Airamir Padilha de Castro and Wolfgang Hanke
Universitat Hohenheim, Instut fur Physiologie – 230, Garbenstrasse 30, 70599 Stuttgart, Germany.

ABSTRACT

In this century, the IT technology will spread intelligent systems based on cameras, sensors and computers across all fields of the human endeavor. The systematization of knowledge will reach new levels of organization and applications. Scientific knowledge will not be an exception. In this paper we present the results of validation tests made with the in vitro retina model in order to propose the systematization of pharmacological knowledge in experimental platforms supplied with data banks. Data banks can be made either for the speeding up of pre-clinical research or for the control of quality of pure substances or pharmaceutical preparations. These applications and other implementations of using the retinal spreading model in pharmacological research will be useful for the users, manufacturers and authorities of regulation of public health.

Keywords:

Retinal spreading depression, pharmacology, quality control, generica, Brazil.