The Open Pharmacology Journal

2012, 6 : 45-51
Published online 2012 October . DOI: 10.2174/1874143601206010045
Publisher ID: TOPHARMJ-6-45

Primary Sclerosing Cholangitis - Current Issues in Clinical Practice

L. Corless and H. Tsai
Department of Gastroenterology, Castle Hill Hospital Cottingham UK.

ABSTRACT

Aims:

To review current issues in the diagnosis and treatment of primary sclerosing cholangitis.

Methods:

search of PubMed using the terms “primary sclerosing cholangitis”, “PSC”, “cholangitis” and “cholestasis”, as well as by review of current guidelines from the major international liver societies.

Results:

Primary sclerosing cholangitis is still a challenging condition to diagnose and manage, but newer imaging modalities like MRCP and timing of liver transplantation point the way forward.

Keywords:

Primary sclerosing cholangitis, ulcerative colitis.